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Invitrogen™ LECT1 Monoclonal Antibody (394002)
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Product Code. 30533695
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Quantity:
100 μg
Unit Size:
100µg
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30533695 100 μg 100µg
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Product Code. 30533695 Supplier Invitrogen™ Supplier No. MA561398

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Description

Mouse Monoclonal Antibody

Reconstitute at 0.5 mg/mL in sterile PBS.

ChM-1 is a cartilage-specific matrix glycoprotein that stimulates the growth of chondrocytes. ChM-1 inhibits angiogenesis by disrupting the tube formation of endothelial cells and thus is responsible for the avascular nature of cartilage. ChM-1 is strongly expressed by the proliferating and hypertrophic zones in the epiphyseal plate of long bones. ChM-1 accumulates in the interterritorial matrix around the lacunae. During development, downregulation of ChM-1 permits angiogenesis and ultimately bone formation on the cartilage template. ChM-1 expression is downregulated in the presence of several growth factors including TGFβ2, FGF2 and PTHLH. ChM-1 expression may also play a role in the hypovascularity and chondroid formation of pleomorphic adenomas. The gene encoding human ChM-1 maps to chromosome 13q14-q21.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LECT1
Applications Western Blot
Classification Monoclonal
Clone 394002
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with trehalose and no preservative
Gene CNMD
Gene Accession No. O75829
Gene Alias BRICD3; BRICHOS domain containing 3; CHM1; Chm-1; Chmi; CHM-I; Chondromodulin; Chondromodulin 1; chondromodulin I; chondromodulin-1; Chondromodulin-I; Chondrosurfactant protein; CH-SP; Cnmd; LECT1; leukocyte cell derived chemotaxin 1; leukocyte cell-derived chemotaxin 1; multiple myeloma tumor suppressor 1; MYETS1
Gene Symbols CNMD
Host Species Mouse
Immunogen Mouse myeloma cell line NS0-derived recombinant human Chondromodulin-1 mature chain, Glu215-Val333.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11061
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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