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Leptomycin B, MedChemExpress

Product Code. 16429737
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5 μg
Unit Size:
5µg
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16429737 5 μg 5µg
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Product Code. 16429737 Supplier Medchem Express Supplier No. HY16909

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Description

MedChemExpress Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle.

Leptomycin B (CI 940

Specifications

Chemical Name or Material Leptomycin B
Physical Form Solid
CAS 87081-35-4
Color White
Quantity 5 μg
Purity Grade Notes Research
Molecular Formula C33H48O6
For Use With (Application) Cancer-programmed cell death
Synonym CI 940 LMB
Solubility Information DMSO : 100 mg/mL (184.94 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMILES O=C(O)/C=C(C)/C[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)/C=C(C)/C=C/C[C@@H](C)/C=C(CC)\C=C\[C@H]1[C@@H](C)C=CC(O1)=O)=O
Molecular Weight (g/mol) 540.73
Formula Weight 540.73
Percent Purity 98.98%
Grade Research
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