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Lonafarnib, MedChemExpress

Product Code. 16496318
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16496318 10 mg 10mg
16458907 5 mg 5mg
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Product Code. 16496318 Supplier Medchem Express Supplier No. HY15136
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Estimated Shipment: 25-09-2026
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Description

MedChemExpress Lonafarnib (Sch66336) is a potent and orally active farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras, K-ras and N-ras with IC50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities.

Lonafarnib (Sch66336) is a potent and orally active farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras, K-ras and N-ras with IC50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities.

Specifications

Chemical Name or Material Lonafarnib
CAS 193275-84-2
Color White
Purity Grade Notes Research
Molecular Formula C27H31Br2ClN4O2
Quantity 10 mg
Synonym Sch66336
Solubility Information DMSO : 50 mg/mL (78.27 mM; Need ultrasonic)
SMILES O=C(N1CCC(CC(N2CCC([C@@H]3C4=C(Br)C=C(Cl)C=C4CCC5=CC(Br)=CN=C53)CC2)=O)CC1)N
Molecular Weight (g/mol) 638.82
Formula Weight 638.82
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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