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Ly-6C Rat anti-Mouse, FITC, Clone: AL-21, BD
Rat Monoclonal Antibody
Brand: BD Biosciences 561085
This item is not returnable.
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Description
The AL-21 monoclonal antibody specifically binds to a non-polymorphic determinant of Ly-6C, a 14-17 kDa GPI-linked cell-surface antigen found on some monocyte/macrophage populations, granulocytes, endothelial cells, plasma cells, and thymocyte, NK-cell, and T-subsets. Mice with the Ly-6.2 alloantigen (eg, AKR, C57BL, C57BR, C57L, C58, DBA/2, PL, SJL, SWR, 129) have subsets of CD8+ and CD4+ Ly-6C+ T cells, while Ly-6.1 strains (eg, A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+ Ly-6C+ T cells.Upregulation of Ly-6C expression on CD8+ T cells by interferons α and β and poly (I:C) has been described,and Ly-6C is a memory marker on CD8+ T cells.
Specifications
| Ly-6C | |
| Monoclonal | |
| 0.5mg/mL | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Not reported | |
| 25 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| AL-21 | |
| FITC | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Mouse | |
| IgM κ |
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