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PeproTech MDC Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
Rabbit Polyclonal Antibody
Brand: PeproTech 500-P176BT-25UG
This item is not returnable.
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Description
AA Sequence of recombinant protein: GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITVKNRD ICADPRQVWV KKLLHKLS. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine MDC (CCL22). Anti-Murine MDC (CCL22)-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect mMDC by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine MDC (500-P176) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant mMDC. Western Blot: To detect mMDC by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant mMDC is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P176BT-1MG will be provided as 2 x 500 μg
CCL22 may play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Also, it is a chemotactic for monocytes. dendritic cells and natural killer cells. CCL22 is a mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4.
Specifications
| MDC | |
| Polyclonal | |
| Biotin | |
| CCL22 | |
| A-152E5.1; Abcd1; ABCD-1; Activated B and dendritic cell-derived; AW060611; CC chemokine ABCD-1; CC chemokine STCP-1; C-C motif chemokine 22; C-C motif chemokine ligand 22; Ccl22; chemokine (C-C motif) ligand 22; DC/B-CK; DCBCK; dendritic cell and B cell derived chemokine; macrophage-derived chemokine; MDC; MDC(1-69); MDC(3-69); MDC(5-69); MDC(7-69); MGC108943; MGC34554; RP24-69A20.1; Scya22; small inducible cytokine A22; SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1) (ACTIVATED B AND DENDRITIC CELL-DERIVED); small inducible cytokine subfamily A (Cys-Cys) member 22; small inducible cytokine subfamily A (Cys-Cys), member 22; small inducible cytokine subfamily A, member 22; small inducible cytokine subfamily A22; small-inducible cytokine A22; STCP-1; stimulated T cell chemotactic protein 1; stimulated T-cell chemotactic protein 1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 20299 | |
| -20°C | |
| Lyophilized |
| ELISA, Western Blot | |
| 0.1-1.0 mg/mL | |
| PBS with no preservative | |
| O88430 | |
| CCL22 | |
| E.coli-derived Recombinant Murine MDC (CCL22). | |
| 25 μg | |
| Primary | |
| Mouse | |
| Antibody |
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