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Mertansine, MedChemExpress
Description
Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC).
Specifications
Specifications
| Chemical Name or Material | Mertansine |
| CAS | 139504-50-0 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C35H48ClN3O10S |
| Quantity | 5 mg |
| Synonym | DM1 Maytansinoid DM1 |
| Solubility Information | DMSO : 62.5 mg/mL (84.66 mM; Need ultrasonic) |
| SMILES | C[C@]1([C@@](CC(N(C(C=C2C=C3OC)=C3Cl)C)=O)([H])OC([C@H](C)N(C)C(CCS)=O)=O)[C@H]([C@@H]([C@](OC4=O)([H])C[C@]([C@](/C=C/C=C(C)/C2)([H])OC)(N4)O)C)O1 |
| Molecular Weight (g/mol) | 738.29 |
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Research purposes only
Product Title
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