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Invitrogen™ MESDC2 Monoclonal Antibody (513802)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561572
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
MESDC2 chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4. May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells.
Specifications
| MESDC2 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 5% trehalose and no preservative | |
| Q14696 | |
| Mesd | |
| E. coli-derived recombinant human MESDC2, Ala34-Leu234. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| Western Blot | |
| 513802 | |
| Unconjugated | |
| Mesd | |
| 2210015O11Rik; AW537813; BOCA; KIAA0081; LDLR chaperone MESD; LRP chaperone MESD; MESD; Mesdc2; MESDM; mesoderm development candiate 2; mesoderm development candidate 2; Mesoderm development LRP chaperone MESD; Mesoderm development protein; mKIAA0081; msd; renal carcinoma antigen NY-REN-61; UNQ1911/PRO4369 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 23184 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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