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  6. MKP-2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1G1C12, Proteintech

MKP-2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1G1C12, Proteintech

Product Code. 16828145 Shop All Proteintech Products
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150 μL
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16828145 20 μL 20µL
16818145 150 μL 150µL
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Product Code. 16828145 Supplier Proteintech Supplier No. 663491IG20UL

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Description

Mouse Monoclonal Antibody

DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.

Specifications

Antigen MKP-2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone 1G1C12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene DUSP4
Gene Accession No. Q13115, Q62767, Q8BFV3
Gene Alias dual specificity phosphatase 4, DUSP4, HVH2, MAP kinase phosphatase 2, MKP 2, MKP2, MKP-2, TYP, VH2
Gene Symbols Dusp4
Host Species Mouse
Immunogen MKP-2 Fusion Protein Ag1206
Purification Method Protein G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100514374, 1846, 319520, 60587
Target Species Rat, Human, Mouse, Pig
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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