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Invitrogen™ MLH3 Polyclonal Antibody
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Product Code. 16613005 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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16613005 100 μL 100µL
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Product Code. 16613005 Supplier Invitrogen™ Supplier No. PA5106564

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MLH3.

This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MLH3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MLH3
Gene Accession No. Q9UHC1
Gene Alias AV125803; BB126472; CAE; CAE1; cell surface glycoprotein; connexin 50; connexin-50; CTRCT1; CX50; CZP1; DNA mismatch repair protein Mlh3; gap junction alpha 8; gap junction alpha-8 protein; gap junction membrane channel protein alpha-8; gap junction protein alpha 8; gap junction protein alpha 8 50kDa; GJA8; HNPCC7; lens fiber protein MP70; lens intrinsic membrane protein MP70; MGC138372; MLH3; MP70; mutL homolog 3; mutL homolog 3 (E coli); MutL protein homolog 3
Gene Symbols MLH3
Host Species Rabbit
Immunogen A synthesized peptide derived from human MLH3(Accession Q9UHC1), corresponding to amino acid residues E526-S576.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 217716, 27030, 314320
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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