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MMV008138, MedChemExpress

Product Code. 16415846
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Product Code. 16415846

Brand: Medchem Express HY123561

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MedChemExpress MMV008138 is a species-selective IspD (enzyme 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase)-targeting antimalarial agent, with an IC50 of 44 nM for PfIspD (P. falciparum IspD). MMV008138 inhibits the growth of P. falciparum Dd2 strain with an IC50 of 250 nM.

MMV008138 is a species-selective IspD (enzyme 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase)-targeting antimalarial agent, with an IC50 of 44 nM for PfIspD (P. falciparum IspD). MMV008138 inhibits the growth of P. falciparum Dd2 strain with an IC50 of 250 nM.

Specifications

Chemical Name or Material MMV008138
Physical Form Solid
CAS 1679333-73-3
Color Yellow
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C18H14Cl2N2O2
For Use With (Application) Neuroscience-Neuromodulation
Solubility Information DMSO : 125 mg/mL (346.05 mM; Need ultrasonic)
SMILES O=C([C@@H]1CC2=C([C@@H](C3=CC=C(Cl)C=C3Cl)N1)NC4=C2C=CC=C4)O
Molecular Weight (g/mol) 361.22
Formula Weight 361.22
Percent Purity 99.48%
Grade Research
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Research purposes only

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