Invitrogen™ Monkeypox Virus A4L (MPXV/USA/2022/MA001) Recombinant Rabbit Monoclonal Antibody (HL2555)

Description

Monkeypox Virus A4L (MPXV/USA/2022/MA001) Recombinant Monoclonal Antibody for Western Blot, ICC/IF

The Monkeypox Virus A4L gene encodes a protein that is considered essential for the replication and virulence of the monkeypox virus, a member of the Orthopoxvirus genus, which also includes the variola virus responsible for smallpox. The A4L protein is a DNA-dependent RNA polymerase subunit, playing a crucial role in the transcription of viral DNA into mRNA, which is necessary for the production of viral proteins and the replication of the virus within the host cell. Monkeypox virus causes a disease in humans that is similar to smallpox but generally less severe, characterized by fever, rash, and lymphadenopathy. Due to its critical function in the viral replication cycle, the A4L protein is a significant target for antiviral drug development and research. Understanding the structure and function of the A4L protein can provide insights into the molecular mechanisms of monkeypox virus replication and pathogenesis, aiding in the development of effective therapeutic strategies and diagnostic tools to combat monkeypox infections.