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  6. Monomethyl auristatin E, MedChemExpress

Monomethyl auristatin E, MedChemExpress

Product Code. 16471756
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Product Code. 16471756 Supplier Medchem Express Supplier No. HY15162

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Description

MedChemExpress Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types.

Monomethyl auristatin E (MMAE

Specifications

Chemical Name or Material Monomethyl auristatin E
Physical Form Powder
CAS 474645-27-7
Color White
Quantity 500 mg
Purity Grade Notes Research
Molecular Formula C39H67N5O7
Synonym MMAE SGD-1010 Vedotin
Solubility Information Ethanol : 50 mg/mL (69.64 mM; Need ultrasonic) ∣DMSO : ≥ 48 mg/mL (66.85 mM)
SMILES CC(C)[C@H](NC)C(N[C@H](C(N([C@@H]([C@@H](C)CC)[C@@H](CC(N1CCC[C@@]1([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C2=CC=CC=C2)O)=O)=O)OC)C)=O)C(C)C)=O
Molecular Weight (g/mol) 717.98
Formula Weight 717.98
Percent Purity 97.54%
Grade Research
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