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Invitrogen™ MVP Recombinant Rabbit Monoclonal Antibody (K01_1U27)
Description
Immunogen sequence: MGPEGQPLGR RVAS.
This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
Specifications
Specifications
| Antigen | MVP |
| Applications | Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | K01_1U27 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 150mM NaCl, 40% glycerol, 0.05% BSA and 0.01% sodium azide; pH 7.4 |
| Gene | MVP |
| Gene Accession No. | Q14764 |
| Gene Alias | 2310009M24Rik; LRP; Lung resistance-related protein; major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP |
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