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  6. 16342705

Invitrogen™ NeuroD1 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA585775

Product Code. 16342705

  • 516.00 € / 100µL

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Description

Description

Keep as concentrated solution. Predicted reactivity: Mouse (100%), Rat (100%). Positive Control: U87-MG, SK-N-SH, IMR32, SK-N-AS, mouse fetal brain, rat cerebellum. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

NeuroD1
Polyclonal
Unconjugated
NEUROD1
Basic helix-loop-helix factor 1; basic helix-loop-helix transcription factor; Beta2; beta-cell E-box transactivator 2; beta-cell E-box transcriptional activator 2; BHF1; BHF-1; bHLHa3; Class A basic helix-loop-helix protein 3; MODY6; neuro d1; Neurod; Neurod1; neurogenic differentiation 1; neurogenic differentiation factor 1; neurogenic helix-loop-helix protein NEUROD; neuronal differentiation 1
Rabbit
Antigen affinity chromatography
RUO
18012, 29458, 4760
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
1.63 mg/mL
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Q13562, Q60867, Q64289
NEUROD1
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of mouse NeuroD1. The exact sequence is proprietary.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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