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NSC 87877, Tocris Bioscience™

Product Code. 30001301
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50 mg
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Product Code. 30001301 Supplier Tocris Bioscience Supplier No. 2613/50

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Description

Potent inhibitor of shp2 and shp1 PTP

Potent inhibitor of shp2 and shp1 protein tyrosine phosphatases (PTP) (IC50 values are 0.318, 0.355, 1.691, 7.745, 65.617, 84.473 and 150.930 μM for shp2, shp1, PTP1B, HePTP, DEP1, CD45 and LAR respectively). Inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
TRUSTED_SUSTAINABILITY

Specifications

CAS 56990-57-9
Molecular Formula C19H13N3O7S2
Quantity 50 mg
Synonym 8-hydroxy-7-6-sulfo-naphthalen-2-ylazo-quinoline-5-sulfonic acid, 8-hydroxy-7-6-sulfo-2-naphthyl azo-5-quinolinesulfonic acid, ncistruc1_001562, ncistruc2_001738, 8-hydroxy-7-6-sulfonaphthalen-2-yl diazenyl-quinoline-5-sulfonic acid, 8-hydroxy-7-6-sulfonaphthalen-2-yl diazenyl quinoline-5-sulfonic acid, 8-hydroxy-7-e-6-sulfo-2-naphthyl azo quinoline-5-sulfonic acid, 7e-8-oxo-7-6-sulfonaphthalen-2-yl hydrazinylidene quinoline-5-sulfonic acid
InChI Key BIQBDHSYQMHHPU-CJLVFECKSA-N
SMILES C1=CC2=C(C(=O)C(=NNC3=CC4=C(C=C3)C=C(C=C4)S(=O)(=O)O)C=C2S(=O)(=O)O)N=C1
IUPAC Name (7E)-8-oxo-7-[(6-sulfonaphthalen-2-yl)hydrazinylidene]quinoline-5-sulfonic acid
Molecular Weight (g/mol) 459.447
PubChem CID 5459322
Formula Weight 459.45
Percent Purity >98%
Chemical Name or Material NSC 87877
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