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NVP 231, MedChemExpress
Description
NVP 231 is a potent, specific, and reversible ceramide kinase (CerK) inhibitor(IC50=12 nM) that competitively inhibits binding of ceramide to CerK. NVP 231 induces cell apoptosis by increasing DNA fragmentation and caspase-3 and caspase-9 cleavage.
Specifications
Specifications
| Chemical Name or Material | NVP 231 |
| Physical Form | Solid |
| CAS | 362003-83-6 |
| Color | Off-White |
| Quantity | 100 mg |
| Purity Grade Notes | Research |
| Molecular Formula | C25H25N3O2S |
| For Use With (Application) | Cancer-Kinase/protease |
| Solubility Information | DMSO : ≥ 41 mg/mL (95.01 mM) |
| SMILES | O=C(C1(C[C@@H](C2)C3)C[C@@H]3C[C@@H]2C1)NC4=CC=C5N=C(NC(C6=CC=CC=C6)=O)SC5=C4 |
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Research purposes only
Product Title
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