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NVP 231, MedChemExpress

Product Code. 16446366
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Product Code. 16446366 Supplier Medchem Express Supplier No. HY13945

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MedChemExpress NVP 231 is a potent, specific, and reversible ceramide kinase (CerK) inhibitor(IC50=12 nM) that competitively inhibits binding of ceramide to CerK. NVP 231 induces cell apoptosis by increasing DNA fragmentation and caspase-3 and caspase-9 cleavage.

NVP 231 is a potent, specific, and reversible ceramide kinase (CerK) inhibitor(IC50=12 nM) that competitively inhibits binding of ceramide to CerK. NVP 231 induces cell apoptosis by increasing DNA fragmentation and caspase-3 and caspase-9 cleavage.

Specifications

Chemical Name or Material NVP 231
Physical Form Solid
CAS 362003-83-6
Color Off-White
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C25H25N3O2S
For Use With (Application) Cancer-Kinase/protease
Solubility Information DMSO : ≥ 41 mg/mL (95.01 mM)
SMILES O=C(C1(C[C@@H](C2)C3)C[C@@H]3C[C@@H]2C1)NC4=CC=C5N=C(NC(C6=CC=CC=C6)=O)SC5=C4
Molecular Weight (g/mol) 431.55
Formula Weight 431.55
Percent Purity 98.91%
Grade Research
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