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OSI-930, MedChemExpress
Description
OSI-930 is an orally selective inhibitor of Kit, KDR and CSF-1R (c-Fms) with IC50s of 80 nM, 9 nM and 15 nM, respectively. OSI-930 also moderately inhibits Flt-1, c-Raf, Lck and low activity against PDGFRα/β, Flt-3 and Abl. OSI-930 has antitumor activity.
Specifications
Specifications
| Chemical Name or Material | OSI-930 |
| CAS | 728033-96-3 |
| Color | Light Yellow |
| Purity Grade Notes | Research |
| Molecular Formula | C22H16F3N3O2S |
| Quantity | 10 mg |
| Solubility Information | DMSO : 50 mg/mL (112.75 mM; Need ultrasonic) |
| SMILES | O=C(C1=C(NCC2=CC=NC3=CC=CC=C23)C=CS1)NC4=CC=C(OC(F)(F)F)C=C4 |
| Molecular Weight (g/mol) | 443.44 |
| Formula Weight | 443.44 |
| Show More |
Research purposes only
Product Title
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