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OXER1 Rabbit anti-Human, Polyclonal, Proteintech

Product Code. 16816695 Shop All Proteintech Products
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150 μL
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150µL
20µL
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16816695 150 μL 150µL
16826695 20 μL 20µL
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Product Code. 16816695 Supplier Proteintech Supplier No. 552021AP150UL

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Description

Rabbit Polyclonal Antibody

This antibody is specific to OXER1.

TG1019 is a G protein-coupled receptor that functions as a chemoattractant for eosinophils and neutrophils. TG1019 is expressed in various tissues except the brain, with the highest expression in liver, kidney, peripheral leukocyte, lung and spleen. TG1019 interacts with the protein OXE to form TG1019/OXE, a Galpha i/o protein-coupled receptor. Signals from TG1019 are transduced via a Galpha i/o protein to PLC/calcium, MEK/ERK and PI3K/Akt pathways. Signal transduction from TG1019 following stimulation with 5-oxo-6E,8Z,11Z,14Z eicosatetraenoic acid (5-oxo-ETE) induces intracellular calcium mobilization and rapid activation of MEK/ERK and PI3K/Akt pathways. TG1019 also may play a role in downregulating cAMP production.

Specifications

Antigen OXER1
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene OXER1
Gene Accession No. Q8TDS5
Gene Alias G protein coupled receptor 170, GPCR, GPR170, OXER1, oxoeicosanoid (OXE) receptor 1, Oxoeicosanoid receptor 1, TG1019
Gene Symbols OXER1
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 165140
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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