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P62/SQSTM1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16838474 Shop All Proteintech Products
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150 μL
20 μL
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20µL
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16838474 20 μL 20µL
16828474 150 μL 150µL
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Product Code. 16838474 Supplier Proteintech Supplier No. 184201AP20UL

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Rabbit Polyclonal Antibody

The molecular weight of p62 is predicted to be 48/ 38 kDa (depending on the isoform), while western blot analyses using this antibody detects the bands around 45-48 kDa and 60-62 kDa, respectively.

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Specifications

Antigen P62/SQSTM1
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Flow Cytometry, Immunofluorescence, Immunocytochemistry
Classification Polyclonal
Concentration 0.29 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SQSTM1
Gene Accession No. O08623, Q13501, Q64337
Gene Alias P62, sequestosome 1, SQSTM1, Ubiquitin binding protein p62
Gene Symbols Sqstm1
Host Species Rabbit
Immunogen P62/SQSTM1 Fusion Protein Ag13131
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 113894, 18412, 8878
Target Species Human, Rat, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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