missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ Pannexin 1 Monoclonal Antibody (720505)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561763
This item is not returnable.
View return policy
Description
Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.
The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
Specifications
| Pannexin 1 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| P60570, Q96RD7, Q9JIP4 | |
| PANX1 | |
| E. coli-derived recombinant human Pannexin-1, Pro298-Asp376. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG2b |
| Western Blot | |
| 720505 | |
| Unconjugated | |
| PANX1 | |
| AI847747; innexin; MRS1; Pannexin 1; pannexin-1; Panx1; px1; UNQ2529; UNQ2529/PRO6028 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 24145, 315435, 55991 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction