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Invitrogen™ PAR6 Polyclonal Antibody

Description
PA5-19770 targets PAR6 in IF and WB applications and shows reactivity with Human samples. The PA5-19770 immunogen is synthetic peptide conjugated to KLH derived from within residues 300 to the C-terminus of Human PAR6. PA5-19770 detects PAR6 which has a predicted molecular weight of approximately 37 kDa.
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 domain and a semi-Cdc42/Rac interactive binding domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Specifications
Specifications
| Antigen | PAR6 |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% sodium azide; pH 7.4 |
| Gene | PARD6A |
| Gene Accession No. | Q9NPB6 |
| Gene Alias | 0710008C04Rik; 2610010A15Rik; PAR6; Par-6; par-6 (partitioning defective 6,) homolog alpha; PAR-6 alpha; par-6 family cell polarity regulator alpha; par-6 partitioning defective 6 homolog alpha; PAR6A; PAR-6A; PAR6alpha; PAR6C; Pard6a; Partitioning defective 6 homolog alpha; partitioning defective protein 6A; partitioning defective-6 homolog alpha; partitioning-defective protein 6; similar to Partitioning defective-6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40); tax interaction protein 40; TAX40; Tax-interacting protein 40; Tip-40 |
| Gene Symbols | PARD6A |
| Show More |
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