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PAT-1251, MedChemExpress

Product Code. 16456827
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Product Code. 16456827

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Description

MedChemExpress PAT-1251 is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively); PAT-1251 is used in the research of fibrotic diseases.

PAT-1251 is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively)

Specifications

Chemical Name or Material PAT-1251
CAS 2007885-39-2
Color White
Purity Grade Notes Research
Molecular Formula C18H17F4N3O3
Quantity 5 mg
Solubility Information DMSO : ≥ 130 mg/mL (325.54 mM)
SMILES FC(F)(F)C1=NC(OC2=CC(C(N3C[C@@H](F)[C@H](O)C3)=O)=CC=C2)=CC(CN)=C1
Molecular Weight (g/mol) 399.34
Formula Weight 399.34
Percent Purity 95.11%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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