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  6. Invitrogen™ PCBP4 Recombinant Mouse Monoclonal Antibody (K1E075_14F9)

Invitrogen™ PCBP4 Recombinant Mouse Monoclonal Antibody (K1E075_14F9)

Product Code. 30830390
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30830390 50 μL
30830056 100 μL
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Product Code. 30830390 Supplier Invitrogen™ Supplier No. MA565953

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Description

Mouse Recombinant Monoclonal Antibody

Immunogen sequence: EPELSITLTL RMLMHGKEVG SIIGKKGETV KRIREQSSAR ITISEGSCPE RITTITGSTA AVFHAVSMIA FKLDEDLCAA PANGGNVSRP PVTLRLVIPA SQCGSLIGKA GTKIKEIRET TGAQVQVAGD LLPNSTERAV TVSGVPDAII LCVRQICAVI LESPPKGATI PYHPSLSLGT VLLSANQGFS VQGQYGAVTP AEVTKLQQLS SHAVPFATPS VVPGLDPGTQ TSSQEFLVPN DLIGCVIGRQ GSKISEIRQM SGAHIKIGNQ AEGAGERHVT Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 32%, Pig - 99%, Cynomolgus monkey - 100%.

MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family also referred to as alpha-CPs, bind to RNA with specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements. Its overexpression in transfected cells results in the suppression of cell proliferation by inducing apoptosis and cell cycle arrest in G2-M. Decreased expression of one isoform of MCG10 has been observed in many forms of lung cancer, leading to speculation that MCG10 can act as a tumor suppressor. Multiple alternatively spliced isoforms of MCG10 have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PCBP4
Applications Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Clone K1E075_14F9
Concentration 0.57 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.5% BSA, 50% glycerol and 0.09% sodium azide
Gene PCBP4
Gene Accession No. P57723
Gene Alias 1200003L19Rik; alpha CP-4; alpha-CP4; AlphaCP-4; alphaCP-4 protein; CBP; LIP4; LYST-interacting protein; MCG10; Pcbp4; poly(rC) binding protein 4; poly(rC)-binding protein 4; RNA binding protein MCG10
Gene Symbols PCBP4
Host Species Mouse
Immunogen Recombinant human PCBP4 (aa 11-290).
Purification Method Protein A
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57060
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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