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Invitrogen™ PDCD6 Polyclonal Antibody
Sheep Polyclonal Antibody
Brand: Invitrogen™ PA5149115
This item is not returnable.
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Description
Reconstitute at 0.2 mg/mL in sterile PBS.
An increased intracellular Ca2+ concentration induces apoptotic cell death. Transiently elevated Ca2+ concentrations are required for glucocorticoid-mediated and T cell receptor-mediated pathways, leading to T cell apoptosis. ALG-2 (for apoptosis-linked gene 2) is a Ca2+ -binding protein that participates in regulatory events occuring late in the apoptotic program and where several death signals converge. ALG-2 is a protein expressed in normal brain, and to a greater extent in ischemic brain. The ALG-2 protein contains five EF-hand-like motifs and shares homology with members of the penta EF-hand family, which includes Calpain small subunits sorcin and Grancalcin.
Specifications
| PDCD6 | |
| Polyclonal | |
| Unconjugated | |
| Pdcd6 | |
| Alg2; alg-2; ALG-257; Apoptosis-linked gene 2 protein; Apoptosis-linked gene 2 protein homolog; AV299538; MA-3; PDCD6; PEF1B; PMP41; probable calcium-binding protein ALG-2; programmed cell death 6; programmed cell death protein 6; PS2 | |
| Sheep | |
| Antigen affinity chromatography | |
| RUO | |
| 10016, 18570, 308061 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| Western Blot | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| G3V7W1, O75340, P12815 | |
| Pdcd6 | |
| E. coli-derived recombinant human PDCD6, Met1-Val189. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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