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Periostin Mouse anti-Human, Mouse, Rat, Clone: 1A11A3, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66491-1-IG-150UL
This item is not returnable.
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Description
Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor beta 1(TGF beta 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.Specifications
| Periostin | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q15063, Q62009 | |
| Postn | |
| Periostin Fusion Protein Ag14487 | |
| 150 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1A11A3 | |
| Unconjugated | |
| POSTN | |
| OSF 2, OSF2, Osteoblast specific factor 2, PDLPOSTN, periostin, PN, POSTN, RP11 412K4.1 | |
| Mouse | |
| Protein G | |
| RUO | |
| 10631, 361945, 50706 | |
| -20°C | |
| Liquid |
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