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Phospho-ALOX5 (Ser523) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA14628
Code : LD
Additional Details : Weight : 0.01000kg
Description
This antibody is predicted to react with non-human primate based on 100% sequence homology. This antibody is specific for the ∽80 kDa 5-LO phosphorylated at Ser523 in Western blots of rat hippocampal lysates.
This gene encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.Specifications
| Phospho-ALOX5 (Ser523) | |
| Polyclonal | |
| 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5 | |
| P09917, P12527, P48999 | |
| ALOX5 | |
| Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser523 of human ALOX5 conjugated to KLH | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Western Blot | |
| Unconjugated | |
| ALOX5 | |
| 5 - Lipoxygenase; 5-lipoxygenase; 5LO; 5-LO; 5-LOX; 5LPG; 5LX; AI850497; ALOX5; Arachidonate 5-lipoxygenase; arachidonic 5-lipoxygenase alpha-10 isoform; arachidonic 5-lipoxygenase delta-10-13 isoform; arachidonic 5-lipoxygenase delta-13 isoform; arachidonic 5-lipoxygenase delta-p10 isoform; arachidonic acid 5-lipoxygenase; F730011J02; leukotriene A4 synthase; LOG5; LOW QUALITY PROTEIN: arachidonate 5-lipoxygenase; lox5; LOX-5; LOX5A; polyunsaturated fatty acid 5-lipoxygenase; RP11-67C2.3 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 11689, 240, 25290 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |