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Phospho-GluR1 (Ser845) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen 368300
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Description
GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter, L-glutamate, induces a conformation change that leads to the opening of the cation channel and converts the chemical signal to an electrical impulse. Then, the receptor desensitizes rapidly and enters a transiet inactive state characterized by the presence of a bound agonist. In the presence of CACNG4, CACNG7, or CACNG8 GluR1 shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Specifications
| Phospho-GluR1 (Ser845) | |
| Polyclonal | |
| Gria1 | |
| AMPA 1, AMPA-selective glutamate receptor 1, GLUH1, GluR-1, GluR-A, GluR-K1, GLUR1, GLURA, Glutamate receptor 1, Glutamate receptor ionotropic, AMPA 1, glutamate receptor, ionotropic, AMPA 1, GRIA1, HBGR1, MGC133252 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 50592 | |
| -20°C | |
| Liquid |
| ELISA, Immunofluorescence, Immunohistochemistry, Western Blot | |
| Unconjugated | |
| P19490 | |
| Gria1 | |
| Synthetic phospho-peptide derived from the rat GluR1 protein. | |
| 150 μL | |
| Primary | |
| Rat | |
| Antibody | |
| IgG |
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