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Invitrogen™ Phospho-LAT (Tyr220) Recombinant Rabbit Monoclonal Antibody (24GB1375)
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Rabbit Recombinant Monoclonal Antibody

146.00 € - 500.00 €

Specifications

Antigen Phospho-LAT (Tyr220)
Clone 24GB1375
Concentration 2.35 mg/mL
Content And Storage -20°C
Applications Western Blot, Immunocytochemistry
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
30275144
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Invitrogen™
MA557159
100 μL
500.00 €
100µL
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30276558
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Invitrogen™
MA557160
20 μL
146.00 €
20µL
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Description

Description

Phospho-LAT (Tyr220) Recombinant Monoclonal Antibody for Western Blot

LAT (Linker for Activation of T cells) is a 36-38 kDa double-palmitoylated transmembrane adaptor protein expressed by T cells, pre-B cells, NK cells, mast cells and platelets. After immunoreceptor triggering, LAT becomes multiply tyrosine-phosphorylated by Syk-, Src-, or Tec-family kinases, providing docking sites for downstream signaling molecules. LAT is essential for TCR-dependent T cell- and FcepsilonRI-dependent mast cell activation, as well as for maturation of early thymocytes. It is also involved in NK cell signaling and platelet activation.
Specifications

Specifications

Phospho-LAT (Tyr220)
2.35 mg/mL
Western Blot, Immunocytochemistry
Unconjugated
Rabbit
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
O43561, O54957, O70601
16797, 27040, 81511
A synthesized peptide derived from human Phospho-LAT (Tyr220) (aa 213-227).
Antibody
24GB1375
-20°C
Recombinant Monoclonal
Liquid
IgG
Human, Mouse, Rat
LAT
36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; Lat; LAT1; linker for activation of T cells; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells; linker for activation of T-cells family member 1; linker protein; p36-38; pp36
LAT
Primary
Affinity chromatography
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