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Invitrogen™ Phospho-PKA alpha/beta/gamma (Thr197) Recombinant Rabbit Monoclonal Antibody (24GB1650)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA556936
This item is not returnable.
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Description
Phospho-PKA alpha/beta/gamma (Thr197) Recombinant Monoclonal Antibody for Western Blot, Flow
Protein kinase A (PKA, cAMP-dependent protein kinase) is a key element of a ubiquitous signaling pathway important in the cell cycle, cellular communication, memory formation and behavior. PKA is composed of two catalytic (PKAc; Protein Kinase A catalytic subunit) and two regulatory subunits (PKAr). Upon binding cAMP, the complex dissociates to PKAr dimer and two activated PKAc ser/thr protein kinase catalytic monomers. The released PKAc can translocate into the nucleus and exert a regulatory role in the activation of multiple nuclear hormone receptors. However, PKAc-mediated activation of tonicity-dependent gene expression is cAMP independent. Humans express three types of PKAc subunit - PKAc alpha is present in most human tissues, PKAc beta and gamma are tissue-specific, the later is found in testes.
Specifications
| Phospho-PKA alpha/beta/gamma (Thr197) | |
| Recombinant Monoclonal | |
| 0.5 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P05132, P17252, P22612, P22694, P27791, P68181, P68182 | |
| PRKACA, PRKACB, PRKACG | |
| A synthesized peptide derived from human Phospho-PKA C (Thr197) (aa 190-204). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Flow Cytometry, Western Blot | |
| 24GB1650 | |
| Unconjugated | |
| PRKACA | |
| BDPLT19; cAMP-dependent protein kinase catalytic beta subunit isoform 4ab; cAMP-dependent protein kinase catalytic subunit alpha; cAMP-dependent protein kinase catalytic subunit alpha, isoform 1; cAMP-dependent protein kinase catalytic subunit beta; cAMP-dependent protein kinase catalytic subunit gamma; KAPG; PKA C-alpha; PKA C-beta; PKA C-gamma; PKACA; PKACB; PKACg; PPNAD4; PRKACA; PRKACB; PRKACG; protein kinase A catalytic subunit; protein kinase A catalytic subunit beta; protein kinase cAMP-activated catalytic subunit alpha; protein kinase cAMP-activated catalytic subunit beta; protein kinase cAMP-activated catalytic subunit gamma; protein kinase, cAMP-dependent, alpha catalytic subunit; protein kinase, cAMP-dependent, beta catalytic subunit; protein kinase, cAMP-dependent, catalytic, alpha; protein kinase, cAMP-dependent, catalytic, beta; protein kinase, cAMP-dependent, catalytic, gamma; protein kinase, cAMP-dependent, gamma catalytic subunit; serine(threonine) protein kinase | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 18747, 18749, 25636, 293508, 5566, 5567, 5568 | |
| -20°C | |
| Liquid |
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