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Invitrogen™ Phospho-PRAS40 (Thr246) Recombinant Rabbit Monoclonal Antibody (3A1F3)
Rabbit Recombinant Monoclonal Antibody
176.00 € - 436.00 €
Specifications
| Antigen | Phospho-PRAS40 (Thr246) |
|---|---|
| Clone | 3A1F3 |
| Concentration | 4.5 mg/mL |
| Content And Storage | -20°C, Avoid Freeze/Thaw Cycles |
| Applications | ELISA, Western Blot |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
30282376
|
Invitrogen™
MA558237 |
20 μL |
176.00 €
20µL |
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|
30283943
|
Invitrogen™
MA558238 |
100 μL |
436.00 €
100µL |
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Description
Immunogen sequence: LNT(p)SD.
The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia. AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can induce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells.Specifications
| Phospho-PRAS40 (Thr246) | |
| 4.5 mg/mL | |
| ELISA, Western Blot | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3 | |
| Q96B36, Q9D1F4 | |
| 67605, 84335 | |
| A synthetic phosphorylated peptide around T246 of human AKT1S1/PRAS40 (NP_001265088.1). | |
| Antibody |
| 3A1F3 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Recombinant Monoclonal | |
| Liquid | |
| IgG | |
| Human, Mouse | |
| AKT1S1 | |
| 1110012J22Rik; 40 kDa proline-rich AKT substrate; AI227026; AKT1 substrate 1; AKT1 substrate 1 (proline rich); AKT1 substrate 1 (proline-rich); akt1s1; Lobe; Lobel; OTTHUMP00000196756; OTTHUMP00000196760; PKB/Akt substrate 40; Pras; PRAS40; Proline-rich AKT substrate; proline-rich AKT1 substrate 1 | |
| AKT1S1 | |
| Primary | |
| Protein A |
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