missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Phospho-SHIP1 (Tyr1021) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA538393
This item is not returnable.
View return policy
Description
SHIP-1 p145 (SH2-containing-inositol phosphatase), an effector molecule, associates with activated Fms oncogenes. SHIP-1 contains two phosphotyrosine-binding domains (PTB), a unique amino terminal SH2 domain, a proline-rich region, and two highly conserved motifs found among inositol phosphate 5-phosphatases. SHIP-1 displays both phosphatidylinositol 3,4,5-triphosphate and inositol 1, 3, 4, 5 -tetrakisphosphate polyphosphate 5-phosphatase activity. Evidence suggests that SHIP-1 may modulate Ras signaling in addition to inositol signaling pathways.
Specifications
| Phospho-SHIP1 (Tyr1021) | |
| Polyclonal | |
| Unconjugated | |
| INPP5D | |
| SHIP, SHIP1, SIP-145, hp51CN, SH2 containing inositol phosphatase, SH2 domain-containing inositol 5′-phosphatase 1, SH2 domain-containing inositol phosphatase 1, SH2 domain-containing inositol-5′-phosphatase 1, SHIP-1, inositol polyphosphate-5-phosphatase of 145 kDa, p150Ship, phosphatidylin | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 16331, 3635 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q92835, Q9ES52 | |
| INPP5D | |
| A synthetic phosphopeptide derived from human SHIP1 around the phosphorylation site of Tyr1021 (P-L-YP-G-S) | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction