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Invitrogen™ PIM2 Monoclonal Antibody (447023)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA561427
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
PIM2 is a proto-oncogene which phosphorylates BAD, which partially inhibits its apopotopic function. PIM proteins (PIM-1, PIM-2 and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 is highly homologous to Pim-1 with similar oncogenic functions. PIM-2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. PIM2 expression is negatively regulated by growth factor depletion. Increased levels of PIM-2 has also been observed in certain cancers.
Specifications
| PIM2 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| Q62070, Q9P1W9 | |
| PIM2 | |
| E. coli-derived recombinant human PIM2, Met1-Pro311. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG2b |
| Western Blot | |
| 447023 | |
| Unconjugated | |
| PIM2 | |
| DXCch3; PIM2; Pim-2; pim-2 oncogene; Pim-2 proto-oncogene, serine/threonine kinase; pim-2h; proto-oncogene Pim-2 (serine threonine kinase); proviral integration site 2; serine/threonine protein kinase pim-2; serine/threonine-protein kinase pim-2 | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 11040, 18715, 317366 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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