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Invitrogen™ PLA1 Polyclonal Antibody
Description
A recommended positive control is SK-N-SH cell lysate. At least two isoforms are known to exist; this antibody will recognize both isoforms. POU2F3 antibody is not expected to cross-react with other members of the POU domain class 2 family.
This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011].
Specifications
Specifications
| Antigen | PLA1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% sodium azide |
| Gene | POU2F3 |
| Gene Accession No. | P31362, P42571, Q9UKI9 |
| Gene Alias | 11-Oct; Epoc-1; FLJ40063; LOC553427 protein; MGC126698; Oct11; oct-11; Oct-11a; octamer-binding protein 11; Octamer-binding transcription factor 11; OTF11; OTF-11; PLA1; PLA-1; POU class 2 homeobox 3; POU domain transcription factor OCT11a; POU domain, class 2, transcription factor 3; POU transcription factor; POU2F3; Rov 1 pou-homeodomain protein; Skin; Skin-1a; Skn-1a; Skn-li; Transcription factor PLA-1; transcription factor Skn-1; zgc:136377; zgc:158534 |
| Gene Symbols | POU2F3 |
| Show More |
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