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PPM1F Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00 € - 410.00 €

Specifications

Antigen PPM1F
Concentration 0.13 mg/mL
Applications Western Blot, Immunocytochemistry, Immunoprecipitation, Immunofluorescence
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16896824
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Proteintech
17020-1-AP-20UL
20 μL
145.00 €
20µL
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16886824
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Proteintech
17020-1-AP-150UL
150 μL
410.00 €
150µL
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Description

Description

PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis.
Specifications

Specifications

PPM1F
Western Blot, Immunocytochemistry, Immunoprecipitation, Immunofluorescence
Unconjugated
Rabbit
Mouse, Rat, Human
P49593, Q8CGA0, Q9WVR7
287931, 68606, 9647
PPM1F Fusion Protein Ag10186
Primary
-20°C
PPM1F
0.13 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
CaM kinase phosphatase, CaMKPase, FEM 2, hFEM 2, KIAA0015, Partner of PIX 2, POPX2, PPM1F, Protein fem 2 homolog, Protein phosphatase 1F
Ppm1f
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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Documents

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