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pS2/pNR-2 Estrogen-Regulated Protein Ab-1, Mouse Monoclonal Antibody,Lab Vision™ Epredia™

Provide accurate, reproducible results with the Epredia™ pS2/pNR-2 Estrogen-Regulated Protein Ab-1, Mouse Monoclonal Antibody.

Brand:  Epredia MS-111-P

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Product Code. 12659026

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Description

Description

pS2 is a cysteine-rich, 6.5kDa protein found in both estrogen-dependent (breast tumors) and estrogen-independent tissues (normal stomach mucosa). About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is primarily expressed in estrogen receptor-positive breast tumors.

Host Species: Mouse

Clone: pS2.1

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: aa 54-84

Immunogen: A synthetic 31-mer peptide aa 54-84 (KGCCFDDTVRGVPWCFYPNTIDVPPEEECEF) from the C-terminus of human pS2 protein

Molecular Weight: 6.5kDa

Cellular Localization: Cytoplasmic Antibody to pS2 is reportedly useful in identifying a subset of estrogen-dependent breast tumors which may respond to endocrine therapy.

Recommended for:

  • Immunohistochemistry

Note:

USA: RUO; Int'l: RUO

TRUSTED_SUSTAINABILITY
Specifications

Specifications

pS2/pNR-2 Estrogen-Regulated Protein Ab-1
Monoclonal
200μg/mL
Mouse
1 mL
Cancer and Tumor Biology
Human
IgG1
Immunohistochemistry (Paraffin)
pS2.1
Unconjugated
A Synthetic 31-mer peptide aa 54-84 (KGCCFDDTVRGVPWCFYPNTIDVPPEEECEF) from the C-terminus of human pS2 protein
RUO
Primary
Concentrated
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