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Invitrogen™ PSPN Monoclonal Antibody (240839)
Rat Monoclonal Antibody
Brand: Invitrogen™ MA561158
This item is not returnable.
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Description
Reconstitute at 0.5 mg/mL in sterile PBS.
Persephin is a disulfide-linked, homodimeric, neurotrophic factor structurally related to GDNF, artemin, and neurturin. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Persephin signals through a multicomponent receptor system, composed of RET and one of four GFR alpha (alpha1-alpha4) receptors. The GFRalpha4 was first identified in chicken, and was later shown to be the preferential binding subunit for persephin. Persephin promotes the survival of ventral midbrain dopaminergic neurons and motor neurons after sciatic nerve oxotomy, and, like GDNF, promotes ureteric bud branching. However, in contrast to GDNF and neurturin, persephin does not support the survival of peripheral neurons.
Specifications
| PSPN | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with trehalose and no preservative | |
| O70300 | |
| PSPN | |
| E. coli-derived recombinant mouse Persephin, Ala61-Gly156. | |
| 500 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a |
| Western Blot | |
| 240839 | |
| Unconjugated | |
| PSPN | |
| Persephin; PSP; Pspn | |
| Rat | |
| Protein A/G | |
| RUO | |
| 19197 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
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