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NBN (phospho S343), Rabbit anti-Human, Polyclonal Antibody, Abnova™
Description
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq
Specifications
Specifications
| Antigen | NBN |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic phosphopeptide of NBN. |
| Dilution | Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) |
| Gene | NBN |
| Gene Alias | AT-V1/AT-V2/ATV/FLJ10155/MGC87362/NBS/NBS1/P95 |
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For Research Use Only
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