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Invitrogen™ RET A883F Recombinant Human Protein

This RET A883F Recombinant Human Protein (658-end) was expressed in insect cells.

Brand:  Invitrogen™ A33506

Additional Details : Weight : 0.01000kg

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Product Code. 15930413

  • 467.00 € / 10µg
Estimated Shipment: 02-12-2022
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Description

Description

  • This RET A883F recombinant human protein (658–end) was expressed in insect cells
  • RET receptor tyrosine kinase or RET proto-oncogene is a member of the cadherin superfamily, which are cell-surface receptors that transduce signals for cell growth and differentiation
  • RET can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement
  • Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia (type IIA), multiple endocrine neoplasia (type IIB), Hirschsprung disease, and medullary thyroid carcinoma
  • RET signaling pathway plays a key role in the molecular mechanisms that orchestrate intestine organogenesis by regulating the development of both the nervous and lymphoid system in the gut
  • RET A883F recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
  • Validated for use with the Z’-LYTE™ assay
  • Available in multiple pack sizes for convenient use
  • Also available in our SelectScreen Kinase Profiling Service
Specifications

Specifications

NP_065681.1
10 µg
aa 658-end
GST Tag
Dry Ice
Recombinant, Active, Cytoplasmic, Mutant
Kinase Assay
74.6 kDa
RET Kinase Family
Yes
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol
Insect
Liquid
Human
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