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Rhosin hydrochloride, MedChemExpress

Product Code. 16495268
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Product Code. 16495268 Supplier Medchem Express Supplier No. HY12646

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Description

MedChemExpress Rhosin hydrochloride is a potent, specific RhoA subfamily Rho GTPases inhibitor. Rhosin hydrochloride specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ∼ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride induces cell apoptosis. Rhosin hydrochloride promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability.

Rhosin hydrochloride is a potent, specific RhoA subfamily Rho GTPases inhibitor. Rhosin hydrochloride specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ∼ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride induces cell apoptosis. Rhosin hydrochloride promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability.

Specifications

Chemical Name or Material Rhosin hydrochloride
Physical Form Solid
CAS 1281870-42-5
Color Yellow
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C20H19ClN6O
For Use With (Application) Cancer-Kinase/protease
Solubility Information DMSO : 100 mg/mL (253.25 mM; Need ultrasonic) ∣H2O : 16.67 mg/mL (42.22 mM; Need ultrasonic)
SMILES O=C(N/N=C/C1=CC=C2N=CC=NC2=C1)[C@H](N)CC3=CNC4=C3C=CC=C4.[H]Cl
Molecular Weight (g/mol) 394.86
Formula Weight 394.86
Percent Purity 99.67%
Grade Research
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Research purposes only

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