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Invitrogen™ ALKBH4 Recombinant Rabbit Monoclonal Antibody (24GB6805)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA556963
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Description
ALKBH4 Recombinant Monoclonal Antibody for Western Blot
Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes (PubMed:23673617). Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration (PubMed:23673617). In addition to proteins, also demethylates DNA: specifically demethylates DNA methylated on the 6th position of adenine (N(6)-methyladenosine) DNA, thereby regulating Polycomb silencing. [UniProt].
Specifications
| ALKBH4 | |
| Recombinant Monoclonal | |
| Unconjugated | |
| ALKBH4 | |
| 2010004B12Rik; ABH4; Abj4; alkB homolog 4, lysine demethylase; alkB homolog 4, lysine demthylase; alkB, alkylation repair homolog 4; alkB, alkylation repair homolog 4 (E. coli); Alkbh4; Alkylated DNA repair protein alkB homolog 4; alpha-ketoglutarate-dependent dioxygenase alkB homolog 4; DNA N6-methyl adenine demethylase ALKBH4; Lysine-specific demethylase ALKBH4; probable alpha-ketoglutarate-dependent dioxygenase ABH4; RGD1308608 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 54784 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 24GB6805 | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q9NXW9 | |
| ALKBH4 | |
| Recombinant protein of human ALKBH4 (aa 2-302). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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