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  6. RPS10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

RPS10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16803794 Shop All Proteintech Products
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150 μL
20 μL
Unit Size:
150µL
20µL
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16803794 20 μL 20µL
16893784 150 μL 150µL
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Product Code. 16803794 Supplier Proteintech Supplier No. 148941AP20UL

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Description

Rabbit Polyclonal Antibody

Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein S10 (RPS10) is a 165 amino acid component of the small ribosomal 40S subunit. While generally found in the cytoplasm, RPS10 can localize to the granular component (GC) region of the nucleolus. For this to occur, methylation by PRMT5 is required as well as an interaction with NPS1. Defects in RPS10 are the cause of Diamond-Blackfan anemia type 9 (DBA9). It is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of maligcy.

Specifications

Antigen RPS10
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.17 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RPS10
Gene Accession No. P46783, P63325, P63326
Gene Alias 40S ribosomal protein S10, ribosomal protein S10, RPS10
Gene Symbols RPS10
Host Species Rabbit
Immunogen RPS10 Fusion Protein Ag6683
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6204, 67097, 81773
Target Species Human, Rat, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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