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S1PR1/EDG1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 55133-1-AP-150UL
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Description
The antibody is specific to S1PR1.
S1P1 is a G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that is coupled to the G(i) subclass of heteromeric G proteins. S1P1 signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. It plays an important role in cell migration via its role in the reorganization of the actin cytoskeleton and formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. S1P1 is required for normal chemotaxis toward sphingosine 1-phosphate, normal embryonic heart development, and normal cardiac morphogenesis.Specifications
| S1PR1/EDG1 | |
| Polyclonal | |
| Unconjugated | |
| S1PR1 | |
| CD363, CHEDG1, D1S3362, ECGF1, EDG 1, EDG1, S1P receptor 1, S1P receptor Edg 1, S1P1, S1PR1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 13609, 1901 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 0.77 mg/mL | |
| 0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| O08530, P21453 | |
| S1PR1 | |
| Peptide | |
| 150 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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