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Invitrogen™ SATB2 Recombinant Rabbit Monoclonal Antibody (3B12)
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Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA560698

Product Code. 30534093

  • 459.00 € / 100µL

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Description

Description

SATB2 Recombinant Monoclonal Antibody for IHC (P), ELISA

DNA-binding protein SATB2 binds to DNA at the nuclear matrix- or scaffold associated regions. It is thought to recognize the sugar-phosphate structure of double-stranded DNA. SATB2 is a transcription factor controlling nuclear gene expression by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. It also acts as a docking site for several chromatin remodeling enzymes by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. SATB2 is required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes - probably by modulating BCL11B expression. It is a repressor of Ctip2 and a regulatory determinant of corticocortical connections in the developing cerebral cortex. Mutations in the gene are associate with cleft palate isolated (CPI).
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SATB2
Recombinant Monoclonal
0.4 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q9UPW6
SATB2
A synthesized peptide derived from Human SATB2.
100 μL
Primary
Human
Antibody
IgG
ELISA, Immunohistochemistry (Paraffin)
3B12
Unconjugated
SATB2
DNA-binding protein SATB2; FLJ21474; FLJ32076; GLSS; KIAA1034; KIAA1034-like DNA binding protein; MGC119474; MGC119477; mKIAA1034; RGD1562369; SATB family member 2; SATB homeobox 2; SATB2; special AT-rich sequence binding protein 2; special AT-rich sequence-binding protein 2; two cut domains-containing homeodomain protein
Rabbit
Affinity chromatography
RUO
23314
-20°C or -80°C if preferred
Liquid
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