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Invitrogen™ SCIN Recombinant Rabbit Monoclonal Antibody (23GB4135), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA552658
This item is not returnable.
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Description
The SCIN gene, also known as scinderin, encodes for a calcium-dependent actin filament-severing protein that is involved in the regulation of the cytoskeleton. It plays a significant role in actin filament dynamics, influencing cellular processes such as cell shape, motility, secretion, and division. SCIN has been identified as a novel oncogene, with its abnormal expression strongly correlated to various cancers, including glioma and uterine corpus endometrial carcinoma. Specific mutations like S673F and S381Y in SCIN are linked with poor prognosis and are potential targets for cancer diagnosis, prognosis, and treatment strategies.
Specifications
| SCIN | |
| Recombinant Monoclonal | |
| 0.45 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q60604, Q9Y6U3 | |
| SCIN | |
| A synthesized peptide derived from human SCIN (650-715AA). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 23GB4135 | |
| Unconjugated | |
| SCIN | |
| Adseverin; AW545522; Gelsolin-like protein; KIAA1905; SCIN; Scind; Scinderin | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 20259, 298975, 85477 | |
| -20°C | |
| Liquid |
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