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Invitrogen™ SDPR Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5149062
This item is not returnable.
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Description
Reconstitute at 0.2 mg/mL in sterile PBS.
The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.
Specifications
| SDPR | |
| Polyclonal | |
| Unconjugated | |
| CAVIN2 | |
| caveolae associated protein 2; caveolae-associated protein 2; cavin 2; CAVIN2; cavin-2; EMBL:AAH81956.1}; phosphatidylserine binding protein; phosphatidylserine-binding protein; PS-p68; SDPR; sdpr {ECO:0000312; SDR; serum deprivation response; serum deprivation response protein; serum deprivation-response protein | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 20324, 8436 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Lyophilized |
| Western Blot | |
| 0.2 mg/mL | |
| PBS with trehalose and no preservative | |
| O95810, Q63918 | |
| CAVIN2 | |
| E. coli-derived recombinant human SDPR, Gly2-Val180. | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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