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  6. Invitrogen™ SEMA7A Recombinant Rabbit Monoclonal Antibody (K01_2P42)

Invitrogen™ SEMA7A Recombinant Rabbit Monoclonal Antibody (K01_2P42)

Product Code. 30830399
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Product Code. 30830399 Supplier Invitrogen™ Supplier No. MA565663

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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: QGHLRSGPRI FAVWKGHVGQ DRVDFGQTEP HTVLFHEPGS SSVWVGGRGK VYLFDFPEGK NASVRTVNIG STKGSCLDKR DCENYITLLE RRSEGLLACG TNARHPSCWN LVNGTVVPLG EMRGYAPFSP DENSLVLFEG DEVYSTIRKQ EYNGKIPRFR RIRGESELYT SDTVMQNPQF IKATIVHQDQ AYDDKIYYFF REDNPDKNPE APLNVSRVAQ LCRGDQGGES SLSVSKWNTF LKAMLVCSDA ATNKNFNRLQ DVFLLPDPSG QWRDTRVYGV FSNPWNYSAV CVYSLGDIDK VFRTSSLKGY HSSLPNPRPG KCLPDQQPIP TETFQVADRH PEVAQRVEPM GPLKTPLFHS KYHYQKVAVH RMQASHGETF HVLYLTTDRG TIHKVVEPGE QEHSFAFNIM EIQPFRRAAA IQTMSLDAER RKLYVSSQWE VSQVPLDLCE VYGGGCHGCL MSRDPYCGWD QGRCISIYSS ERSVLQSINP AEPHKECPNP KPDKAPLQKV SLAPNSRYYL SCPMESRHAT YSWRHKENVE QSCEPGHQSP NCILFIENLT AQQYGHYFCE AQEGSYFREA QHWQLLPEDG IMAEHLLGHA CALA Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 29%, Pig - 86%, Cynomolgus monkey - 98%.

CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors - plexin C1 and beta1 integrins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SEMA7A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone K01_2P42
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 0.05% BSA, 40% glycerol, 150mM NaCl and 0.01% sodium azide; pH 7.4
Gene SEMA7A
Gene Accession No. O75326
Gene Alias 2900057C09Rik; CD108; CDw108; H-Sema K1; H-SEMA-K1; H-Sema-L; JMH; JMH blood group antigen; John Milton Hagen blood group H-Sema K1; john-Milton-Hargen human blood group Ag; MGC126692; MGC126696; M-Sema-L; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group); sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A; sema K1; Sema L; SEMA7A; SEMAK1; SEMAL; semaphorin 7A (John Milton Hagen blood group); semaphorin 7A, GPI membrane anchor; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group); Semaphorin K1; semaphorin-7A; Semaphorin-K1; semaphorin-L; Semk1
Gene Symbols SEMA7A
Host Species Rabbit
Immunogen Recombinant protein of human Semaphorin 7a (aa 45-648).
Purification Method Protein A/G
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8482
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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