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Invitrogen™ SH3PXD2A Polyclonal Antibody
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Product Code. 16670585 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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16670585 100 μL 100µL
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Product Code. 16670585 Supplier Invitrogen™ Supplier No. PA5104136

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SH3PXD2A.

Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SH3PXD2A
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Sh3pxd2a
Gene Accession No. O89032, Q5TCZ1
Gene Alias 2310014D11Rik; AA589508; Adapter protein TKS5; adaptor protein TKS5; AI256723; AI413738; C230050L11; EG329070; FISH; Five SH3 domain-containing protein; five SH3 domains; Gm5098; KIAA0418; SH3 and PX domain-containing protein 2A; SH3 and PX domains 2A; SH3 multiple domains 1; SH3 multiple domains protein 1; Sh3md1; SH3PXD2A; Tks5; TSK5; Tyrosine kinase substrate with five SH3 domains
Gene Symbols Sh3pxd2a
Host Species Rabbit
Immunogen A synthesized peptide derived from human SH3PXD2A(Accession Q5TCZ1), corresponding to amino acid residues V105-D155.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14218, 9644
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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