missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ SIGLEC8 Recombinant Human Monoclonal Antibody (18D13)
Human Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA560809
This item is not returnable.
View return policy
Description
SIGLEC8 Recombinant Monoclonal Antibody for IHC (P), ELISA
SIGLEC8 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3-linked sialic acid. and also binds to alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. SIGLEC8 is expressed specifically on eosinophils. The protein contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in downmodulation of cellular responses. The phosphorylated ITIM motif binds to the SH2 domain of PTPN6/SHP-1. The SIGLEC8 gene belongs to the immunoglobulin superfamily.
Specifications
| SIGLEC8 | |
| Recombinant Monoclonal | |
| 1.94 mg/mL | |
| PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4 | |
| Q9NYZ4 | |
| SIGLEC8 | |
| Recombinant Human SIGLEC8 protein. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| ELISA, Immunohistochemistry (Paraffin) | |
| 18D13 | |
| Unconjugated | |
| SIGLEC8 | |
| CDw329; MGC59785; SAF2; SAF-2; sialic acid binding Ig like lectin 8; sialic acid binding Ig-like lectin 8; sialic acid-binding Ig-like lectin 8; Sialoadhesin family member 2; Siglec; SIGLEC8; Siglec-8; SIGLEC8L | |
| Human | |
| Affinity chromatography | |
| RUO | |
| 27181 | |
| -20°C or -80°C if preferred | |
| Liquid |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction