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Invitrogen™ SIK2 Polyclonal Antibody
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Goat Polyclonal Antibody

Brand:  Invitrogen™ PA5149056

Product Code. 30534300

  • 429.00 € / 100µg

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Description

Description

Reconstitute at 0.2 mg/mL in sterile PBS.

SNF1LK2 (QIK) is a serine/threonine kinase and is a salt-inducible kinase that belongs to the AMP-activated protein kinase family. SNF1LK2 negatively regulates CRE-binding protein (CREB) activity by phosphorylating the CREB-specific coactivator transducer of regulated CREB activity (TORC). SIK2 is thought to be part of a signaling cascade that regulates the expression and activity of the insulin-induced genes PGC-1'alpha and UCP-1 in brown adipocytes, impairment of which has been implicated in obesity and insulin resistance in human and animal models. SIK2 has also been reported as a key regulator for neuronal survival after ischemia, suppressing CREB-mediated gene expression after oxygen-glucose deprivation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SIK2
Polyclonal
Unconjugated
SIK2
G630080D20Rik; KIAA0781; LOH11CR1I; QIK; Qin-induced kinase; RGD1559698; salt induceable kinase 2; salt inducible kinase 2; salt-inducible kinase 2; salt-inducible protein kinase 2; salt-inducible serine/threonine kinase 2; serine/threonine-protein kinase SIK2; Serine/threonine-protein kinase SNF1-like kinase 2; Sik2; SIK-2; SNF1-like kinase 2; SNF1LK2
Goat
Antigen affinity chromatography
RUO
23235
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Lyophilized
Western Blot, Immunocytochemistry
0.2 mg/mL
PBS with trehalose and no preservative
Q9H0K1
SIK2
E. coli-derived recombinant human SNF1LK2, Ala663-Leu818.
100 μg
Primary
Human
Antibody
IgG
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