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SLC22A17 Mouse anti-Human, Clone: OTI2D6, liquid, TrueMAB™

Product Code. 17573094
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100 μL
Unit Size:
100µL
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17573094 100 μL 100µL
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Product Code. 17573094 Supplier Origene Technologies Supplier No. TA810195

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Description

Mouse Monoclonal Antibody

The Slc22 family of organic anion and cation transporters (OATs, OCTs, OCTNs) are transmembrane proteins expressed predomitly in kidney and liver. Each contain 12 predicted alpha-helical transmembrane domains (TMDs) and one large extracellular loop between TMDs 1 and 2. Transporters of the SLC22 family function in different ways such as uniporters that mediate facilitated diffusion in either direction (OCTs), as anion exchangers (OAT1, OAT3 and URAT1), and as Na(+)/l-carnitine cotransporter (OCTN2). Slc22 family members participate in the absorption and/or excretion of drugs, xenobiotics, and endogenous compounds in intestine, liver, and kidney, and perform homeostatic functions in brain and heart. Mutations in the Slc22 family may cause specific diseases such as primary systemic carnitine deficiency or idiopathic renal hypouricemia and may change drug absorption or excretion. Recent studies show the expression of Slc22A17 as receptor for Lipocalin 2 is relatively high in hematopoietic stem cells.

Specifications

Antigen SLC22A17
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI2D6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene SLC22A17
Gene Accession No. Q8WUG5
Gene Alias 24p3R, BOCT, BOIT, NGALR, NGALR2, NGALR3, hBOIT
Gene Symbols SLC22A17
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 241-300 of human SLC22A17 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51310
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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